April 5, 2006

Chapter 20 Amino Acids and Proteins

20.6 Protein Structure: Tertiary and Quaternary Levels

Tertiary structure: R group interactions

Quaternary structure: intreactions between two or more polypeptide subunits

Hydrophobic

Hydrophilic

Salt bridges

Hydrogen bonds

Disulfide bonds

Quaternary structure hemoglobin: two a and two b chains: Heme
20.7 Protein Hydrolysis and Denaturation

Heat

Acids and Bases

Organic Compounds

Heavy Metal Ions

Agitation
Homework:

20.3, 20.5, 20.7, 20.9, 20.13, 20.15, 20.17, 20.19, 20.21, 20.23, 20.25, 20.27, 20.29, 20.31, 20.37, 20.39, 20.43, 20.47

Chapter 21 Enzymes and Vitamins

21.1 Biological Catalysts

Definition of a catalyst

Lower activation energy
21.2 Names and Classification of Enzymes

suffix -ase

Classifications

Oxidoreductases

Transferases-transfer of functioanl groups

Hydrolases- hydrolysis reactions

Lyases- addition/removal of a group on double bond without hydrolysis or oxidation

Isomerases-rearrangement of atoms to form isomers

Ligases-combine molecules using ATP
21.3 Enzymes as Catalysts

Mechasim of Enzyme Catalyzed Reaction- Formation of ES complex

Homework:

21.1, 21.3, 21.7, 21.11, 21.13, 21.19, 21.25, 21.27, 21.29, 21.31, 21.41, 21.51, 21.53, 21.65, 21.71, 21.73, 21.85