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Andrew Shedlock

Andrew Shedlock

Department of Biology
College of Charleston
66 George St.
Charleston, SC 29424
(843) 953-7638
shedlockam@cofc.edu

Ph.D., 1997, University of Washington

Research emphasis: Comparative genomics, evolutionary genetics, and conservation biology of marine vertebrates; impact of mobile DNA on eukaryotic genome structure and transcriptome function; systematics of retroelements

Current research projects:

  • annotation, assembly and evolutionary synthesis of DNA repeats for NIH-sponsored amniote genome projects
  • phylogenetic reconstruction of ancestral vertebrate genome structure
  • RNA-seq of tissue-specific gene expression in marine vertebrates
  • de novo and reference-based transcriptome assembly of marine vertebrates
  • systematics and molecular ecology of retroposon insertion polymorphisms in legally protected and commercially important marine species

Selected Publications: 

  • Shedlock, A. M., and S. V. Edwards.  2009.  Amniotes (Amniota). Pp. 373-380 In: The Timetree of Life (S. B. Hedges and S. Kumar, Eds.), Oxford University Press, New York.
  • Shedlock, A. M., C. W. Botka, S. Zhao, J. Shetty,T. Zhang, J. S. Liu, P. J. Deschavanne, and S. V. Edwards. 2007. Phylogenomics of non-avian reptiles and the structure of the ancestral amniote genome. Proc. Natl. Acad. Sci. USA. 104:2767-2772.
  • Shedlock, A. M. 2006. Phylogenomic investigation of CR1 LINE diversity in reptiles.  Systematic Biology 55(6):902-911 [cover article].
  • Shedlock, A. M., K. Takahashi, and N. Okada. 2004. SINEs of speciation: tracking lineages with retroposons. Trends in Ecology and Evolution. 19(10): 545-553.
  • Shedlock, A. M., M. C. Milinkovitch, and N. Okada.  2000.  SINE evolution, missing data, and the origin of whales.  Systematic Biology 49(4):808-817 [cover article].